laboratory evaluation of a rodenticide-insecticide, coumavec®, against rhombomys opimus, the main reservoir host of zoonotic cutaneouse leishmaniasis in iran.

b a ckground: zoonotic cutaneous leishmaniasis is a growing health problem in many rural areas of iran. rhombo mys opimus , the great gerbil, is the main animal reservoir of zcl in the northeast and central part of iran. the aim of the current study was to evaluate the rodenticidal effect of coumavec® (a mixture of coumatetralyl 0.5% and etofenprox 0.5%) on r. opimus under laboratory condition. m e t hods: great gerbils were collected from sejzi rural district, esfahan province, iran. four groups of 19 great ger- bils were treated with the poisoned baits of different concentrations and one group was considered as control. the bating procedure was conducted in three stages: first, second (a week after first) and third (a month after first stage), in each stage baits were offered in 1 day, based on national protocol for rodent control operation in purpose of zcl control. results: the mortality rate for 0.03, 0.0625, 0.125 and 0.25% concentrations in the first stage of baiting were ob- tained 36.8%, 31.5%, 52.6% and 36.8%, in the second stage 47.3%, 52.6%, 68.4% and 52.6%, and in the third stage 52.6%, 63.1%, 68.4% and 57.8% respectively. the maximum and minimum mortality has occurred in 5-6 days and 31-40 days intervals consequently. conclusion: the results of this study showed that, coumavec® has some rodenticidal effects on r. opimus in labo- ratory condition. for the appropriate rodenticide-insecticide contamination of the rodent body and also considering to the economic issues, we suggest the use of 0.125% concentration for rodent control operation in the field condition.